An autumn greeting to all of my valued Customers, Case Club Members and Friends receiving this September edition of our monthly newsletter!

A heartfelt thank you to all of those who continue to support A-M B-Well Inc. by providing themselves and their loved ones the benefits of the highest quality pharmaceutical grade fish oil. Remember we have both PGFO Capsules as well as our hugely popular Liquid Gold!!

This month we have found a few interesting articles on how fish oil may help reverse liver disease as well as protecting alcohol abusers from dementia!

Please enjoy!

Fish oil is safe and effective in reversing liver disease in some

source: http://www.upi.com

Fish oil is safe and effective in reversing liver disease in children with intestinal failure who require intravenous nutrition, U.S. researchers say.

Lead author Dr. Kara Calkins, an assistant professor in the department of pediatrics in the division of neonatology and developmental biology at the University of California, Los Angeles, said children who suffer from intestinal failure, most often caused by a shortened or dysfunctional bowel, are unable to consume food orally. Instead, a nutritional cocktail of sugar, protein and fat made from soybean oil is injected through a small tube in the vein, Calkins said.

Previous studies showed replacing soybean oil with fish oil in intravenous nutrition could reverse intestinal failure-associated liver disease. However, the necessary duration of fish oil treatment has not been established in medical studies.

Calkins and colleagues said for this study, intravenous soybean oil was replaced with intravenous fish oil in 10 patients ages of 2 weeks to 18 years who had advanced intestinal failure-associated liver disease and who were at high risk for death and/or transplant. The researchers compared these subjects with 20 historical controls who had received soybean oil.

The study, published in the Journal of Parenteral and Enteral Nutrition, showed children receiving fish oil had a much higher rate of reversal of liver disease than those who received the standard soybean oil. In fact, after 17 weeks of fish oil, nearly 80 percent of patients experienced a reversal of their liver disease while only 5 percent of the soybean patients experienced a reversal, the study said.

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Fish Oil Could Help Protect Alcohol Abusers from Dementia

source: http://www.sciencedaily.com

A Loyola University Chicago Stritch School of Medicine study suggests that omega-3 fish oil might help protect against alcohol-related dementia.

Previous studies have shown that long-term alcohol abuse increases the risk of dementia. The Loyola study found that in the brain cells of rats exposed to high levels of alcohol, a fish oil compound protected against inflammation and cell death.

The study by Michael A. Collins, PhD, and colleagues was reported Sept. 8 at the 14th Congress of the European Society for Biomedical Research on Alcoholism in Warsaw.

An earlier analysis by Collins and Loyola colleague Edward J. Neafsey, PhD, which pooled the results of 143 studies, found that moderate social drinking may reduce the risk of dementia and cognitive impairment. (Moderate drinking is defined as a maximum of two drinks per day for men and 1 drink per day for women.)

It appears that small amounts of alcohol might, in effect, make brain cells more fit. Alcohol in moderate amounts stresses cells and thus toughens them up to cope with major stresses down the road that could cause dementia. But too much alcohol overwhelms the cells, leading to inflammation and cell death.

In the new study, Collins and colleagues exposed cultures of adult rat brain cells to amounts of alcohol equivalent to more than four times the legal limit for driving. These cell cultures were compared with cultures of brain cells exposed to the same high levels of alcohol, plus a compound found in fish oil called omega-3 docosahexaenoic acid (DHA). Researchers found there was about 90 percent less neuroinflammation and neuronal death in the brain cells exposed to DHA and alcohol than in the cells exposed to alcohol alone.

Further studies are needed to confirm whether fish oil protects against alcohol-related dementia. "Fish oil has the potential of helping preserve brain integrity in abusers," Collins said. "At the very least, it wouldn't hurt them."

But Collins added that best way for an alcohol abuser to protect the brain is, if possible, to quit drinking or cut back to moderate amounts . "We don't want people to think it's okay to take a few fish oil capsules and then continue to go on abusing alcohol."

Collins, principal investigator of the study, is a professor in the Department of Molecular Pharmacology and Therapeutics at Loyola University Chicago Stritch School of Medicine. Co-authors are Neafsey, Nuzhath Tajuddin, MS, and Kwan-Hoon Moon, PhD, of the Stritch School of Medicine; Kimberly Nixon, PhD, of the University of Kentucky; and Hee-Yong Kim, PhD, of the National Institute on Alcohol Abuse and Alcoholism.

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Warmest Regards,

Anne-Marie